Hey there "desk-potato"...We spend a lot more time sitting than people used to, and it's taking a toll on our bodies.  Think about some of these things that happen while you are sitting there reading this...

1.  Weaker bones.  Moving around prompts your body to replace old bone tissue.

2.  Depression and anxiety. Plus, the things we do while sitting also lead to depression.  Stuff like overeating and watching too much TV.

3.  Back and neck pain.  After four hours of sitting, the discs in your spine start to compress.  Which can lead to back and neck issues.

4.  Blood clots.  Your blood moves slower through your legs when you sit all day, which can cause clots . . . also called deep vein thrombosis.  And if a piece of that clot breaks off, it can end up in your heart or brain and KILL you.

Two possible solutions, get a desk that adjusts to either sitting or standing.  Also take some breaks just stretch and walk around, in the long-run you'll be happy that you did.

(Prevention / MedicineNet)